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Wiens,Astrid; Lenzi,Luana; Venson,Rafael; Pedroso,Maria Lúcia Alves; Correr,Cassyano Januário; Pontarolo,Roberto. |
The aim of this study was to conduct a cost-utility study of adefovir, entecavir, interferon alpha, pegylated interferon alpha, lamivudine and tenofovir for chronic hepatitis B in the context of Brazilian Public Health Care System. A systematic review was carried out for efficacy and safety. Another review was performed to collect utility data and transition probabilities between health states. A Markov model was developed in a time horizon of 40 years with annual cycles for three groups of: HBeAg positive, HBeAg negative, and all patients. These strategies were compared to a fourth group that received no treatment. Discount rates of 5% were applied and sensitivity analyses were performed. Tenofovir offered the best cost-utility ratio for the three... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chronic hepatitis B; Economic evaluation; Treatments. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000400006 |
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Barret, Jean. |
Different treatments aiming to cure the grounds, which bad been contaminated by the vibrio P1 "brown-ring", have been carried out on some sites of on-growing, taking place in the Aber Benoit, in Brittany. The tested products were Lime, and an antiseptic "Agroseptil" which positive effects are admitted in pisciculture. The results (growth, survival and the presence of brown-ring), do not point out any difference between the various treatments. However, it looks as if the brownring has appeared latter than on other clam-fields located in the same area.This effect does not seem to be due to the various treatments of the soils, but to the antibiotic bath of the clams bef ore seeding. |
Tipo: Text |
Palavras-chave: Palourde; Tapes philippinarum; Vibrio P1; Sédiment; Anneaux brun; Traitement; Antiseptique; Agroseptil; Chaux; Manila clam; Tapes philippinarum; Vibrio P1; Soil; Brown-ring; Treatments; Antiseptic; Agroseptil; Line. |
Ano: 1992 |
URL: http://archimer.ifremer.fr/doc/00425/53673/54513.pdf |
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Wiens,Astrid; Lenzi,Luana; Grochocki,Mônica Cavichiolo; Correr,Cassyano Januário; Pontarolo,Roberto. |
Treatment for chronic hepatitis B in Brazil are funded by the Ministry of Health and by the state Departments of Health. Clinical protocol and therapeutic guidelines approve the use of adefovir, entecavir, interferon-a, lamivudine, and tenofovir for the treatment of chronic hepatitis B. The aim of this study was to establish the profile of users of these drugs in the state of Paraná. A cross-sectional study was conducted with patients under treatment in Paraná in August 2011. The following data were obtained: gender, hepatitis B used drug, International Classification of Diseases, and regional health unit. The monthly cost of these drugs for the public health system was also calculated. 1,093 patients registered were found, 70% male, and 2.6% co-infected... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Chronic hepatitis B; Users profile; Treatments; Demographic profile. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000400012 |
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